4-Caffeoyl-1,5-quinide (4-caffeoylquinic-1,5-lactone or 4-CQL) is found in roasted coffee beans. It is formed by lactonization of 4-O-caffeoylquinic acid during the roasting process.

It is reported to possess opioid antagonist properties in mice.

References


trans4OCaffeoylDquinic acid, hexakisTMS C34H66O9Si6 CID

Structures of caffeoyl and dicaffeoyl quinic acids 17. Download

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Effect of 3,4diOcaffeoyl quinic acid on H 2 O 2 /Fe 2+mediated

The chemical structure of 5Ocaffeoylquinic acid (a),... Download